Choosing the Right Granulation Equipment for Your Manufacturing Goals

When it comes to solid dosage manufacturing, granulation is one of the most critical steps. Whether you're scaling up a new product, improving tablet uniformity, or enhancing flowability, the right granulation equipment can significantly impact product quality, process efficiency, and regulatory compliance.

With a wide range of equipment available—each serving distinct manufacturing needs—how do you choose what’s best for your operation? Let’s break it down.

What Is Granulation, and Why Does Equipment Choice Matter?

Granulation is the process of converting fine powders into free-flowing, compressible granules—ideal for tablet or capsule formulation. The method you choose directly affects:

Powder flowability

Granule size and uniformity

Moisture sensitivity

Content uniformity

Production scale and cost

That’s why selecting the right granulation equipment is not just a technical decision—it’s a strategic one.

Types of Granulation Equipment

At Chamunda Pharma Machinery Pvt. Ltd., we offer high-performance granulation machines designed to meet diverse needs in pharmaceutical, nutraceutical, and chemical manufacturing.

1. High Shear Mixer Granulator (RMG)

Best For: Wet granulation of cohesive powders

How It Works: Uses intense mechanical agitation and binder addition to form granules quickly

Key Benefits:
- Fast processing
- Uniform granules
- Easy cleaning (CIP options available)

Chamunda’s RMG models feature precise control systems, pneumatic discharge, and stainless-steel GMP-compliant designs—ideal for high-output tablet manufacturing.

2. Fluid Bed Granulator / Dryer

Best For: Drying wet granules, granulation of heat-sensitive powders.

How It Works: Air suspends and fluidises the powder while spraying the binder solution.

Key Benefits:
- Uniform drying
- Ideal for moisture control
- Energy-efficient

Fluid bed systems are a great match with RMGs in continuous or batch processing environments.

3. Roller Compactor

Best For: Dry granulation of moisture-sensitive products.

How It Works: Compacts powder between rollers to form ribbons, which are then milled.

Key Benefits:
- No liquid binder needed
- Minimal heat generation
- Lower operating costs

Chamunda's roller compactors are perfect for companies focused on cost-effective, solvent-free production.

4. Multi Mill / Oscillating Granulator

Best For: Size reduction, post-granulation screening.

How It Works: Reduces particle size and removes oversized granules.

Key Benefits:
- Versatile
- Compact design
- Low maintenance

Often used as a supporting piece of equipment in larger granulation setups.

Factors to Consider When Choosing Granulation Equipment

Every manufacturing environment is different. Here are the key factors to consider:

Factor	Why It Matters	Suggested Equipment
Product Moisture Sensitivity	Avoids degradation from wet processes	Roller Compactor
Batch Size / Scale	Impacts equipment size and throughput	RMG (for high output), Multi Mill (for pilot)
Product Uniformity	Affects dosage accuracy	RMG + Fluid Bed Dryer
Cleaning & Compliance	Especially important in pharma / GMP settings	Chamunda’s CIP-enabled RMGs
Budget Constraints	Equipment cost + operating cost	Roller Compactor, Multi Mill

Real-World Use Case: RMG + Fluid Bed System

Many of our pharmaceutical clients use a combo setup: High Shear Mixer Granulator for wet granulation followed by Fluid Bed Dryer for moisture removal. This results in:

Consistent granule size

Fast batch turnaround

Easy scale-up from R&D to production

It’s an ideal setup for high-quality tablet manufacturing.

Why Choose Chamunda’s Granulation Equipment?

At Chamunda Pharma Machinery Pvt. Ltd., we engineer our equipment with decades of manufacturing experience and strict adherence to GMP standards. Our machines are known for:

Precision controls

High energy efficiency

Modular designs for scale-up

Easy integration with upstream/downstream equipment

Clean-in-Place (CIP) features for hygiene compliance

Final Thoughts: Let’s Find the Right Fit for You

Selecting the right granulation equipment means balancing your production goals with product characteristics, compliance needs, and ROI expectations.

Still unsure what’s right for your facility? Talk to our application experts—we’ll help you assess your needs and customise the perfect solution.👉 Contact Us or explore our range of Granulation Equipment.